RT Journal Article
SR Electronic
T1 Diffuse Metabolic Abnormalities in Reversible Posterior Leukoencephalopathy Syndrome
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 833
OP 837
VO 23
IS 5
A1 Eichler, Florian S.
A1 Wang, Paul
A1 Wityk, Robert J.
A1 Beauchamp, Norman J.
A1 Barker, Peter B.
YR 2002
UL http://www.ajnr.org/content/23/5/833.abstract
AB Summary: Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging. Widespread metabolic abnormalities, consisting of increased choline and creatine levels and mildly decreased N-acetylaspartate, occurred in regions with both normal and abnormal MR imaging appearances. In one case for which proton MR spectroscopic imaging follow-up was available, all metabolite levels had returned to normal by 2 months. Proton MR spectroscopic imaging may be helpful for the diagnosis and investigation of the underlying pathophysiology of reversible posterior leukoencephalopathy syndrome.