Monoclonal Antibodies: What the Diagnostic Neuroradiologist Needs to Know

R Alsufayan, C Hess, T Krings - American Journal of …, 2023 - Am Soc Neuroradiology
Monoclonal antibodies have become increasingly popular as novel therapeutics against a
variety of diseases due to their specificity, affinity, and serum stability. Due to the nearly …

Monoclonal antibodies as neurological therapeutics

P Gklinos, M Papadopoulou, V Stanulovic… - Pharmaceuticals, 2021 - mdpi.com
Over the last 30 years the role of monoclonal antibodies in therapeutics has increased
enormously, revolutionizing treatment in most medical specialties, including neurology …

A new era for monoclonal antibodies with applications in neurology

CA Sirbu, MC Ghinescu… - Experimental and …, 2021 - spandidos-publications.com
Medical research continues to focus on developing specific treatment strategies, including
biological products that are effective and have a good safety profile. Due to their novelty, an …

Neurological complications of therapeutic monoclonal antibodies: trends from oncology to rheumatology

C Gill, S Rouse, RD Jacobson - Current Neurology and Neuroscience …, 2017 - Springer
Abstract Purpose of Review This review is to describe the scope of neurological
complications associated with monoclonal antibody-based therapies, applied across …

Monoclonal antibody therapies and neurologic disorders

JC Novak, AE Lovett-Racke, MK Racke - Archives of neurology, 2008 - jamanetwork.com
The role of monoclonal antibody (mAb) therapies in treating medical conditions has
expanded tremendously since its inception in the 1970s, and their use in neurologic …

[HTML][HTML] Safety profile and practical considerations of monoclonal antibody treatment

BC Estruch - Neurología (English Edition), 2013 - Elsevier
Introduction Monoclonal antibodies (mAb) are immunoglobulins specially designed to act
against specific targets, in such a way that their administration stops a specific pathogenic …

Therapeutic Antibodies in Neurological Diseases: Witnessing the Continuation of the Impressive Success in Neuro-Immunotherapies

MC Dalakas, H Wiendl - Neurotherapeutics, 2022 - Springer
This is the second time in the past 6 years that both of us have been involved as Guest
Editor or contributors to a special issue of Neurotherapeutics dedicated to immunotherapies …

Neurologic complications of antitumor antibody therapies

TN Kreisl - Current Neurology and Neuroscience Reports, 2008 - Springer
Antibody-based therapy is being explored across a variety of disease types. Several
successes in oncology have become part of standard care for diseases such as colorectal …

Conquering the barriers: are antibody therapeutics feasible for CNS indications?

D Stanimirovic, K Kemmerich - Future Neurology, 2015 - Future Medicine
The major hurdles on the development path of CNS therapeutics include an inherent
complexity of the CNS, highly restricted drug access to CNS targets by the blood–brain …

Clinically useful monoclonal antibodies in treatment

E Drewe, RJ Powell - Journal of clinical pathology, 2002 - jcp.bmj.com
Monoclonal antibodies have been used in clinical diagnosis for many years but it is only
now that these agents are being licensed for clinical treatments. This review will focus on UK …