Deep-learning convolutional neural networks accurately classify genetic mutations in gliomas

P Chang, J Grinband, BD Weinberg… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The World Health Organization has recently placed new
emphasis on the integration of genetic information for gliomas. While tissue sampling …

[HTML][HTML] Prediction of IDH and TERT promoter mutations in low-grade glioma from magnetic resonance images using a convolutional neural network

R Fukuma, T Yanagisawa, M Kinoshita, T Shinozaki… - Scientific reports, 2019 - nature.com
Identification of genotypes is crucial for treatment of glioma. Here, we developed a method to
predict tumor genotypes using a pretrained convolutional neural network (CNN) from …

Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging

J Cluceru, Y Interian, JJ Phillips, AM Molinaro… - Neuro …, 2022 - academic.oup.com
Background Diagnostic classification of diffuse gliomas now requires an assessment of
molecular features, often including IDH-mutation and 1p19q-codeletion status. Because …

Combining radiomics and deep convolutional neural network features from preoperative MRI for predicting clinically relevant genetic biomarkers in glioblastoma

E Calabrese, JD Rudie, AM Rauschecker… - Neuro-oncology …, 2022 - academic.oup.com
Background Glioblastoma is the most common primary brain malignancy, yet treatment
options are limited, and prognosis remains guarded. Individualized tumor genetic …

[PDF][PDF] A novel fully automated MRI-based deep-learning method for classification of 1p/19q co-deletion status in brain gliomas

CGB Yogananda, BR Shah, FF Yu… - Neuro-oncology …, 2020 - academic.oup.com
Background One of the most important recent discoveries in brain glioma biology has been
the identification of the isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion …

Retracted: A novel fully automated MRI-based deep-learning method for classification of IDH mutation status in brain gliomas

CG Bangalore Yogananda, BR Shah… - Neuro …, 2020 - academic.oup.com
Background. Isocitrate dehydrogenase (IDH) mutation status has emerged as an important
prognostic marker in gliomas. Currently, reliable IDH mutation determination requires …

Combined molecular subtyping, grading, and segmentation of glioma using multi-task deep learning

SR van der Voort, F Incekara, MMJ Wijnenga… - Neuro …, 2023 - academic.oup.com
Background Accurate characterization of glioma is crucial for clinical decision making. A
delineation of the tumor is also desirable in the initial decision stages but is time-consuming …

Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging

K Chang, HX Bai, H Zhou, C Su, WL Bi, E Agbodza… - Clinical Cancer …, 2018 - AACR
Purpose: Isocitrate dehydrogenase (IDH) mutations in glioma patients confer longer survival
and may guide treatment decision making. We aimed to predict the IDH status of gliomas …

[HTML][HTML] Prediction of molecular mutations in diffuse low-grade gliomas using MR imaging features

ZA Shboul, J Chen, K M. Iftekharuddin - Scientific reports, 2020 - nature.com
Diffuse low-grade gliomas (LGG) have been reclassified based on molecular mutations,
which require invasive tumor tissue sampling. Tissue sampling by biopsy may be limited by …

Machine learning for the prediction of molecular markers in glioma on magnetic resonance imaging: a systematic review and meta-analysis

A Jian, K Jang, M Manuguerra, S Liu, J Magnussen… - …, 2021 - journals.lww.com
BACKGROUND Molecular characterization of glioma has implications for prognosis,
treatment planning, and prediction of treatment response. Current histopathology is limited …