BACKGROUND AND PURPOSE: White matter lesions are commonly found in patients with
Fabry disease. Existing studies have shown elevated diffusivity in healthy-appearing brain …

Introduction Fabry disease is a rare lysosomal storage disorder leading to cellular
accumulation of globotriaosylceramide, especially in blood vessels. It is associated with …

Background To identify quantitative MRI parameters associated with diffusion tensor
imaging (DTI) and fast bound‐pool fraction imaging (FBFI) that may detect alterations in gray …

Fabry disease (FD) is a lysosomal storage disorder that is associated with marked
cerebrovascular disease. Conventional MRI shows a progressive load of white matter …

Cerebral white matter pathology is a common CNS manifestation of Fabry disease,
visualized as white matter hyperintensities on MRI in 42–81% of patients. Diffusion tensor …

Methods: Five patients diagnosed with Fabry disease (mean age±SD= 28.2±11.1 years) and
5 age-matched controls were evaluated with the following magnetic resonance image (MRI) …

Background: Fabry disease (FD) is a lysosomal storage disorder associated with marked
cerebrovascular disease. Conventional MRI shows an extensive load of white matter lesions …

Background: Neurologic hallmarks of Fabry disease (FD) include small fiber neuropathy as
well as cerebral micro-and macroangiopathy with premature stroke. Cranial MRI shows …

Central nervous system involvement is a major burden in Fabry disease. Conventional
cranial magnetic resonance imaging (MRI) shows micro‐and macroangiopathic changes …

Objectives To assess structural and metabolic brain changes in subjects affected by Fabry
disease (FD) or carrying the disease mutation. Background FD is an X–linked metabolic …