Purpose To create an inventory of image processing pipelines of arterial spin labeling (ASL)
and list their main features, and to evaluate the capability, flexibility, and ease of use of …

In patients with sickle cell disease (SCD), cerebral blood flow (CBF) is elevated to counteract
anemia and maintain oxygen supply to the brain. This may exhaust the vasodilating …

Background Oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO
2 ) may serve as biomarkers in several diseases. OEF and CMRO 2 can be estimated from …

Background Venous blood oxygenation (Yv), which can be derived from venous blood T 2 (T
2 b), combined with oxygen‐extraction fraction (OEF) and cerebral metabolic rate of oxygen…

Introduction: Deoxygenation-based dynamic susceptibility contrast (dDSC) has previously
leveraged respiratory challenges to modulate blood oxygen content as an endogenous …

… and design, data acquisition, data analysis, interpretation of the data, and manuscript drafting;
Elisabeth Dovern involved in the research setup and manuscript revision; Koen PA Baas …

BACKGROUND AND PURPOSE: White matter lesions are commonly found in patients with
Fabry disease. Existing studies have shown elevated diffusivity in healthy-appearing brain …

Habitual physical activity is beneficial for cerebrovascular health and cognitive function.
Physical exercise therefore constitutes a clinically relevant cerebrovascular stimulus. This study …

Introduction Neurocognitive impairment is a significant problem in patients with sickle cell
disease (SCD), affecting various life domains such as academic achievement, career progress…

Background: Sickle cell disease (SCD) is complicated by cerebral infarctions. These include
silent cerebral infarcts (SCIs) which can be found in 40% of the patients by the age of 20 …