Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Introduction The efficacy and safety of local intra-arterial (IA) thrombolytics during endovascular
thrombectomy (EVT) for large-vessel occlusions is uncertain. We analysed how often IA …

Introduction: Despite improvements in device technology, only one-third of stroke patients
undergoing endovascular thrombectomy (EVT) achieve first-pass effect (FPE). We investigated …

Importance It is unknown whether intravenous thrombolysis using tenecteplase is noninferior
or preferable compared with alteplase for patients with acute ischemic stroke. Objective To …

Background and Objectives Brain frailty may impair the ability of acute stroke patients to cope
with the injury, irrespective of their chronologic age, resulting in impaired recovery. We aim …

Background: Carotid tandem lesions ((TL) ⩾70% stenosis or occlusion) account for 15–20%
of acute stroke with large vessel occlusion. Aims: We investigated the safety and efficacy of …

Background The relationship between the interventionist’s experience and outcomes of
endovascular thrombectomy (EVT) for acute ischemic stroke of the anterior circulation, is unclear…

Introduction We investigated the impact of the Corona Virus Disease 2019 (COVID-19)
pandemic and the resulting lockdown on reperfusion treatments and door-to-treatment times …

Importance Age is a leading predictor of poor outcomes after brain injuries like stroke. The
extent to which age is associated with preexisting burdens of brain changes, visible on …

Background Currently, there are no recommendations regarding the use of heparinized
flush during endovascular thrombectomy (EVT) for acute ischemic stroke. Periprocedural …