Recurrent intracerebral hemorrhage from sarcoid angiitis

J Stroke Cerebrovasc Dis. 1997 Jul-Aug;6(5):373-5. doi: 10.1016/s1052-3057(97)80222-4.

Abstract

Background: Sarcoid affecting the central nervous system may cause granulomatous angiitis. Nevertheless, neurosarcoid manifesting as intracerebral hemorrhage has been infrequently reported.

Case description: A 48-year-old woman with systemic sarcoid developed recurrent intracerebral hemorrhages culminating in death despite treatment with corticosteroids. Pathological examination of the brain revealed inflammatory changes of blood vessels including multinucleated giant cells.

Conclusion: Sarcoid cerebral angiitis may result in intracerebral hemorrhage. This emphasizes one potentially devastating neurological outcome of this disorder.