Abstract
SUMMARY: There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.
ABBREVIATIONS:
- CLOCC
- cytotoxic lesions of the corpus callosum
- COVID-19
- coronavirus disease 2019
- CRP
- C-reactive protein
- RT-PCR
- real-time reverse transcriptase polymerase chain reaction
- SARS-CoV-2
- Severe Acute Respiratory Syndrome coronavirus 2
- © 2020 by American Journal of Neuroradiology
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