Abstract
SUMMARY: Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. We sought to test the ability of contrast-enhanced, high-resolution 3D vessel wall MR imaging to identify vascular inflammation and direct open biopsies of intracranial target vessels and adjacent brain parenchyma. Eight of 9 specimens revealed vascular inflammation. We conclude that vessel wall MR imaging can identify inflamed intracranial vessels, enabling precise localization of biopsy targets.
ABBREVIATIONS:
- CNSV
- CNS vasculitis
- VWMRI
- vessel wall MR imaging
- © 2018 by American Journal of Neuroradiology
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