Abstract
SUMMARY: The TMAs are a group of microvascular occlusive disorders characterized by thrombocytopenia and intravascular hemolysis. Literature review reveals a spectrum of neuroimaging findings, including a single case report of multifocal hemorrhagic infarctions. We present a series of 12 patients with TMA demonstrating a similar pattern of multifocal cortical and subcortical hemorrhagic infarctions.
Abbreviations
- ADC
- apparent diffusion coefficient
- AML
- acute myelogenous leukemia
- CLL
- chronic lymphocytic leukemia
- CNS
- central nervous system
- CTV
- CT venography
- DIC
- disseminated intravascular coagulation
- DWI
- diffusion-weighted imaging
- GRE
- gradient recalled-echo
- HIV
- human immunodeficiency virus
- HUS
- hemolytic uremic syndrome
- mHTN
- malignant hypertension
- MRI
- MR imaging
- MRV
- MR venography
- PRES
- posterior reversible encephalopathy syndrome
- SWI
- susceptibility-weighted imaging
- TMA
- thrombotic microangiopathy
- TTP
- thrombotic thrombocytopenic purpura
- vWF
- von Willebrand factor
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